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Rapidly guide qualified patients to your study
Direct Connect is a revolutionary way to recruit patients for clinical trials. Leveraging one of the world’s largest and fastest-growing patient access marketplaces, SubjectWell connects patients within study-appropriate geographies directly to your study website for registration and prescreening to ensure your trial meets enrollment goals faster.

SubjectWell's unique approach delivers more interested patients
Through the SubjectWell+ platform, sponsors and CROs get access to a real-time view of the anonymized patients sent to your study’s website and the patients’ actions on the site. When using SubjectWell’s hosted pre-screener, sites and sponsors get patient referral counts and the ability to track patient progress throughout the entire enrollment process.
Step 1
SubjectWell finds motivated patients through general awareness advertising.
Step 2
Patients registering in SubjectWell’s network share their conditions and interest in treatment.
Step 3
Advanced machine learning presents relevant trial listings to patients, by condition and location.
Step 4
Interested patients follow the customized pipeline from SubjectWell to your study’s website.
How Direct Connect works
- 1 Unique patient access
- 2 Motivated patients
- 3 Rapid deployment
- 4 Cost efficiency
- 5 Client relationship protection
Unique patient access
Our marketplace combines tens of millions of patients — including including 91% who have never participated in a clinical trial before— with known conditions and a robust media network, bypassing traditional search, social, or display campaigns.

Motivated patients
Patients recruited through Direct Connect are engaged and ready to act, resulting in higher conversion rates compared to traditional channels.

Rapid deployment
Campaigns launch in as little as 1 day with approved creative, enabling studies to reach patients almost immediately.

Cost efficiency
Studies using Direct Connect see a reduction in pre-screening costs, making it a smarter way to allocate your recruitment budget.

Client relationship protection
SubjectWell collaborates with you, ensuring patient referrals align with sponsor needs.

Learn how CROs and Sponsors increased their patient enrollment with SubjectWell’s Direct Connect
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Accelerating patient enrollment with Full-Site Support
9.7x faster patient progressions saves $754,000 and dramatically reduces site11 Jun 2025●3 min -
Transforming dermatology trial recruitment
How SubjectWell’s strategic digital marketing dramatically reduced costs and boosted patient10 Jun 2025●2 min -
Maximizing trial recruitment for peanut allergies
How SubjectWell’s strategic digital marketing dramatically reduced costs and boosted patient09 Jun 2025●2 min -
Evaluating Secondary Screening’s impact on referral quality and study performance
OVERVIEW This Secondary Screening study was created leveraging SubjectWell’s live data sets and19 Feb 2025●3 min